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Results for "

AP site

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Recombinant Proteins

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100714A
    D-AP5
    15+ Cited Publications

    D-APV; D-2-Amino-5-phosphonovaleric acid

    		 iGluR Neurological Disease
    D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors .
    D-AP5
  • HY-135136
    Aldehyde reactive probe TFA

    		Biochemical Assay Reagents Others
    Aldehyde reactive probe (TFA) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA .
    Aldehyde reactive probe TFA
  • HY-119418
    Desketoraloxifene

    		Estrogen Receptor/ERR Cancer
    Desketoraloxifene is an estrogen receptors alpha (ERα) activator at an AP-1 site. Desketoraloxifene can be used for the research of osteoporosis and breast cancer .
    Desketoraloxifene
  • HY-100843
    L-AP6

    L-AP6 is a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons .
    L-AP6
  • HY-157916
    ARP

    Aldehyde reactive probe

    		 Fluorescent Dye Others
    ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 4 nucleotides) .
    ARP
  • HY-100781
    D-AP4

    D-APB; D-2-Amino-4-phosphonobutyric acid
    D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co 2+ influx in cultured cerebellar granule cells (IC50 ≥ 100 μM) .
    D-AP4
  • HY-112902
    OGG1-IN-08
    1 Publications Verification

    		 Others Inflammation/Immunology
    OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1 .
    OGG1-IN-08
  • HY-Y0958
    Methoxyamine hydrochloride

    O-Methylhydroxylamine hydrochloride
    Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .
    Methoxyamine hydrochloride

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